Usage Note
Desserrer is the opposite of serrer (to tighten). Common in practical contexts: desserrer une vis (loosen a screw) or desserrer sa ceinture (loosen one's belt). The reflexive se desserrer means 'to come loose' on its own.
Examples
"Il faut desserrer ce boulon rouillé."
Natural Translation
You need to loosen this rusty bolt.

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