Usage Note
Aspirine is a feminine noun in French and is a trademarked name that has become the generic term, much as in English. In France, aspirin is sold under the brand Aspégic as well as Aspirine. Prendre une aspirine is the standard way to say 'take an aspirin'; note the feminine article.
Examples
"Elle prend une aspirine pour sa migraine."
Natural Translation
She takes an aspirin for her migraine.

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